What is CBD?
Cannabis Sativa L is the genus. Hemp and Cannabis are the classifications. Alike and yet different, the genus produces phyto-cannabinoids that mimic the endocannabinoids we naturally produce in our bodies.
Found in the flowers, seeds, and the stalks of cannabis and hemp. Cannabidiol is among more than 400 compounds found in Cannabis Sativa L. CBD is no longer a little-known molecule, it’s now a potential breakthrough supplement for therapeutic aid and nutrition. Unlike the other cannabinoids, CBD occurs in significant amounts in the plant.
How Cannabidiol Is Made & Produced
Cannabidiol is generally produced in two of the following ways:
Naturally: CBD can be extracted from cannabis and hemp plants. The major difference between cannabis and hemp is the level of THC present. Cannabis is specifically known to have high THC while Hemp has minute traces of THC.
Synthetically: CBD can also be produced synthetically in a lab. Nevertheless, synthetically produced CBD is generally an unregulated substance and its possession is legal outside some specialized circumstances.
How Does Cannabidiol Work?
Cannabidiol is a molecule found in the hemp extract. Some studies have shown that the phyto-cannabinoids extracted from the plant mimic the endocannabinoids that we naturally express in our own bodies.
Cannabinoids and their effects are dependent on the receptor it attaches itself to. Our endocannabinoid system is comprised of 2 identifiable receptors, CB1 and CB2
The CB1, found most predominantly in the brain, derives two responses. One is from THC which induces the psychotropic high, while the other is CBD (Cannabidiol) which is where we are led to believe the interactions lead to less stress and anxiety and is the first step to relieving pain and inflammation that causes pain. This ideology lends itself to the idea that the combination of the supplement and the system response naturally elevates the human disposition acting as an antidepressant.
CB2 receptors function slightly differently as they are found in our central nervous system and immune system. The data in preliminary research is that it is here the relief for physical symptoms occurs such as seizures, spasms, and disease.
In summary, the phyto-cannabinoid, such as CBD, mimics and transmits messages to the endocannabinoid receptors to prompt an outcome. That outcome is the body’s ability to adapt to stress, be it an invasion, inflammation or infection of sorts, also seems to effectively prevent THC’s psychotropic effects, as well as curb stress and anxiety. All of which brings us to “homeostasis”; the condition of optimal performance and balance under the most stressful conditions for the mind and body.
More research is required to enhance the understanding of CBD as it is a new and complex compound. CBD is a “poly-pharmacological”. This means it affects different body parts at once. Therefore, it’s important to understand the interactions of different changes in the user’s body. This can be discovered via more clinical research.
Overview Of Cannabidiol Products
The legalization movement and a demand for natural and healthy alternatives to pharmaceutical drugs have increased medical marijuana’s demand. There are many people that are seeking an alternative found in cannabidiol sources. Since CBD is a natural, legal element in hemp, CBD hemp topical and oil supplements have become very popular.
On their own, cannabinoids are powerful, such as the robust CBD molecule, however each has its own benefits singularly and together, and when several of the extracted molecules are extracted to work together the effect has greater impact to the body and human condition. This is known as “The Entourage Effect”
CBD supplements are available online and in the mainstream market. CBD can be offered as health supplements for all ages, as well as a wide range of beauty and skin products. Click on any of the CBD products below to learn more.
What Are The Effects of CBD & Are There Any Warnings to Know About?
Unlike THC, Cannabidiol is not a psychotropic cannabinoid. Studies have revealed that Cannabidiol has significant neuroprotective and antioxidant properties. This suggests that CBD might be a potential therapeutic aid for a wide range of neurological disorders. Although the FDA has not approved Cannabidiol for any condition, several studies have revealed promising results for different conditions. In addition, anecdotal evidence shows that Cannabidiol products have been used by many people, and CBD as shown that it could potentially relieve pain, anxiety, stress, as well as various symptoms of over 50 different health issues.
This is all relatively impressive, especially considering cannabidiol is an organic and naturally occurring compound that hasn’t been synthetically or chemically altered. Although we can admire CBD for what’s been shared so far, CBD has also shown the potential to relieve and/or lessen the symptoms of over 50 different medical conditions, which we have listed for you immediately below.
While CBD is not known to have any serious side effects, there have been reports that some CBD users have experienced light-headedness, low blood pressure, dry mouth, and drowsiness. Generally, CBD is extremely safe when used responsibly and not used recreationally. That’s because several studies have shown that it does not have significant negative effects regardless of the used dosage or administration method.
Nevertheless, pregnant and breastfeeding women should take special precaution because there is no conclusive research into its safety among them. Additionally, individuals with more serious medical conditions should consult their doctors before they use CBD as a therapeutic aid because high doses may worsen the symptoms in some people.
- Malfait AM, Gallily R, Sumariwalla PF, et al. The non-psychotropic cannabis-constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci USA 2000;97:9561-6.
- Formukong EA, Evans AT, Evans FJ. Analgesic and anti-inflammatory activity of constituents of Cannabis sativa L. Inflammation 1988;12:361-71.
- Esposito G, Scuderi C, Savani C, et al. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. Br J Pharmacol 2007;151:1272-9.
- Iuvone T, Esposito G, De Filippis D, et al. Cannabidiol: a promising new drug for neurodegenerative disorders? CNS Neurosci Ther 2009;15:65-75.
- Bisogno T, Di Marzo Y. The role of the endocannabinoid system in Alzheimer’s severe condition: facts and hypotheses. Curr Pharm Des 2008;14:2299-3305.
- Zuardi AW. Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. Rev Bras Psiquiatr 2008;30:271-80.
- Izzo AA, Borelli F, Capasso R, et al. Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends Pharmacol Sci 2009;30:515-27.
- Booz GW. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med 2011;51:1054-61.